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Sapan

Folkloric
Decoction of wood and bark used for tuberculosis, diarrhea, dysentery, postpartum tonic, skin infections. and anemia.
Seeds used for stomach aches and nervous disorders.
Decoction of wood used postpartum as tonic.

Others
Chiefly used as a dyewood, popular for coloring native fabrics.
In some parts of the Quezon province, a popular colorant for the coconut liquer, lambanog.

Studies
Antimicrobial: Aqueous extract study showed antimicrobial activity against methicillin-sensitive S aureus (MSSA) as well MRSA and suggests a potential to restore the effectiveness of B-lactam antibiotics against MRSA.
Immunosuppressive component: Brazilein, an important immunosuppressive component of CS showed inhibition of T cell proliferation and suppress mice humoral immune response.
Antioxidant: Study results showed significant antioxidant activities of Caesalpinia sappan heartwood extracts.
Anticonvulsant: Study of aqueous MeOH extracts isolated pure compounds sappanchalcone and brazilin which showed remarkable anticonvulsant activity.
Xanthine Oxidase Inhibitors: Study of MeOH extract of Vietnamese CS isolated neoprotosappanin and protosappanin A dimethyl acetal which showed xanthine oxidase inhibitory activity comparable to allopurinol.
Anti-allergic: Study of extracts of CS showed potent inhibitory activity against B-hexosaminidase release as marker of degranulation in rat basophilic leukemic cells. Among the compounds tested, sappanchalcone showed the most potent anti-allergic effect.
Cardioactive effects of Brazilein: Brazilein obtained from CS ethanol extracts showed a positive inotropic action with little effect on heart rate and coronary perfusion, an effect achieved through inhibition of Na-K-ATPase system.

Suggested Readings

(1) Inhibitory effects of Caesalpinia sappan on growth and invasion of methicillin-resistant Staphylococcus aureus / Journal of Ethnopharmacology Vol 91, Issue 1, March 2004, Pages 81-87 / doi:10.1016/j.jep.2003.11.017
(2) Brazilein, an important immunosuppressive component from Caesalpinia sappan L. / International Immunopharmacology
Vol 6, Issue 3, March 2006, Pages 426-432 / doi:10.1016/j.intimp.2005.09.012
(3) Antioxidant Activity of Caesalpinia sappan Heartwood / Biological & Pharmaceutical Bulletin Vol. 26 (2003) , No. 11 1534
(4) Anticonvulsant compounds from the wood of Caesalpinia sappan L. / Archives of Pharmacal Research. Vol 23, Number 4 / August, 2000 / DOI 10.1007/BF02975445
(5) Xanthine Oxidase Inhibitors from the Heartwood of Vietnamese Caesalpinia sappan / Chemical & Pharmaceutical Bulletin Vol. 53 (2005) , No. 8 984
(6) Anti-allergic activity of principles from the roots and heartwood of caesalpinia sappan on antigen-induced -hexosaminidase release / Phytotherapy Research
(7) Study on Cardioactive Effects of Brazilein /

Excerpts from other source:

General Uses: The water kept in Caesalpinia sappan Linn. (Sappan lignum) heartwood is being used in some parts of Kerala as herbal drinking water for its antithirst, blood purifying, antidiabetic, improvement of complexion and several other properties. The use of heartwood as a colouring agent for liquor, wine, meat, fabric, etc. is well established. It has the potential to hit the market as a safe natural colouring agent with good medicinal value for food products, beverages and pharmaceuticals. Sappan is official in India and the Eastern Colonies for use in place of logwood as an astringent. Seeds used for stomach aches and nervous disorders.

Medicinal Uses: Used for purifying blood, quenching thirst, cures jaundice and cough. Good for respiratory ailments, cures wound. As it has medicinal properties similar to Pterocarpus Santalinus it is used in place of this. Its flower is used as a base in fairness creams. It has a capacity to cure Blood Pressure, Heart diseases. The seeds of the plant are used for Stomach aches, and Nervous disorders. This plant is used as a main ingredient in Herbal drinks, widely used in Kerala, and other parts of the country. Indications for treatment include amenorrhea, dysmenorrhea, blood stasis after delivery; pricking pain in the chest and abdomen, traumatic swelling and pain. Decoction of wood and bark used for tuberculosis, diarrhea, dysentery, postpartum tonic, and for skin infections.

General Uses: The water kept in Caesalpinia sappan Linn. (Sappan lignum) heartwood is being used in some parts of Kerala as herbal drinking water for its antithirst, blood purifying, antidiabetic, improvement of complexion and several other properties. The use of heartwood as a colouring agent for liquor, wine, meat, fabric, etc. is well established. It has the potential to hit the market as a safe natural colouring agent with good medicinal value for food products, beverages and pharmaceuticals. Sappan is official in India and the Eastern Colonies for use in place of logwood as an astringent. Seeds used for stomach aches and nervous disorders.

Medicinal Uses: Used for purifying blood, quenching thirst, cures jaundice and cough. Good for respiratory ailments, cures wound. As it has medicinal properties similar to Pterocarpus Santalinus it is used in place of this. Its flower is used as a base in fairness creams. It has a capacity to cure Blood Pressure, Heart diseases. The seeds of the plant are used for Stomach aches, and Nervous disorders. This plant is used as a main ingredient in Herbal drinks, widely used in Kerala, and other parts of the country. Indications for treatment include amenorrhea, dysmenorrhea, blood stasis after delivery; pricking pain in the chest and abdomen, traumatic swelling and pain. Decoction of wood and bark used for tuberculosis, diarrhea, dysentery, postpartum tonic, and for skin infections.

Here’s a couple gems culled from the inbox chaff:

“Caesalpinia sappan, known as Sibukaw Tree, treats hepatitis problems. It also includes diabetes.”

Excerpt from reply or comment re sibukaw:

“with regards to sibukaw tree, it grow near our city and is sold by local streetside herbalist as a remedy to build blood. a decoction of the wood pieces are used. my friend told me that it cured a filipino doctor who came home from the u.s. because he was dying of cancer.”

Main sources:

http://www.stuartxchange.org/Sapan.html

http://www.freewebs.com/mhmgs/sappanwood.html

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