You are currently browsing the category archive for the ‘Anti-angiogenic’ category.


Chemical constituents and characteristics
Amino acids, mucins, mineral salts, starch (32%), vitamins B and C, fixed oil (44%), cucurbitine, acid resin, myosin, vitellin, sugar (4%)
Phytochemical studies indicate two triterpenes, alunsenol and mutiflorenol, with mast cell stabiling effects in rats.
Pulp is a source of vitamins B and C.

• Considered astringent, anthelmintic, aphodisiac, demulcent, diuretic, febrifuge, styptic, tonic.
• Seed is anthelmintic, antiinflammatory.
• Fruit is nutritive, tonic, diuretic, alterative, and styptic.

Parts utilized
Whole fruit with seeds and skin.

Used as vegetable (boiled); sweetened or candied. The fried seeds eaten as a delicacy.
Extracts of Benincasa hispida prevent development of experimental ulcers
• Seeds applied to simple skin eruptions.
• Seeds sans the outer covering used as vermifuge.
• Fruit rind is diuretic; ashes applied to painful wounds.
• Decoction of seed used for vaginal discharges and coughs.
• Fresh juice used as antidote for vegetable poisons.
• In China, popular for its dermatologic and cosmetic applications – for facial blemishes; moisturizing and skin softening use; anti-wrinkle and anti-aging skin properties; preventing sun damage.
• In Japan, kondol is a component of most traditional dermatologic formulations because of its skin regenerative.
• Forms: Tincture or liniments; percolation with propylene glycol or hydro-alcoholic solution.
• In Korea, used for diabetes and kidney problems
• In Ayurveda, used for coughs, epilepsy, asthma, peptic ulcers.
• In India, used for treatment of peptic ulcer: Juice is squeezed out of grated gourd, equal amounts of water is added, taken daily on an empty stomach, with no food intake for 2 to 3 hours. (Source)
• Fruit juice used for insanity, epilepsy.

• Extracts of Benincasa hispida prevent development of experimental ulcers: Used in Ayurveda for peptic ulcers, the study showed extracts of BH may be a natural drug with anti-ulcer activity.
Anti-angiogenic effect of the seed extract of Benincasa hispida Cogniaux: Seed extract of BH supports its anti-angiogenic property through inhibition of endothelial cell proliferation.
Gastroprotective effect of Benincasa hispida fruit extract: Study results were comparable with the omeprazole treated group. Study suggest BH possess significant antiulcer and well as antioxidant property.
EFFECT OF METHANOLIC EXTRACT OF BENINCASA HISPIDA AGAINST HISTAMINE AND ACETYLCHOLINE INDUCED BRONCHOSPASM IN GUINEA PIGS: The ME of BH showed excellent protection against histamine-induced bronchospasm probably through an antihistamin activty (H1 receptor-antagonism).



Used by some as salad component.
A rich source of vitamins A, B, C and D as well as minerals.

• Its multiplicity of uses rates it a herbal cure-all, especially for the treating hepato-biliary disease and as a diuretic.
• in Europe, widely used for gastrointestinal ailments. It is taken as broth with leaves of sorrel and egg yolk for chronic liver congestion.
• Used for its gently laxative effect and as bitter tonic in atonic dyspepsia.
• Promotes appetite and digestion.
• Root preparation used for a variety of conditions: fevers, diabetes, eczema, scurvy, bowel inflammation.
• Pounded poultice of leaves applied to wounds and cuts.
• As a drink: 20 gms of root to a cup of boiling water, take 3-5 glasses a day.
• Juice of the stalk used to remove warts.
• Powdered dried roots used with coffee, and a substitute for coffee when roasted and powdered.
• Extract of dandelion used as remedy for fevers and chills.
• Infusion used to treat anemia, jaundice and nervousness.
• Decoction of root herb taken for scrofula, eczema, scurvy and various skin eruptions.
• Used for eczema and acne.
• Native American Indians have used infusions and decoctions of the root and herb for kidney diseases, dyspepsia and heartburn.
• Traditional Arabian medicine has used it for liver and spleen diseases.
• Chinese medicine used it for hepatitis,bronchitis, pneumonia, as a topical compress for mastitis.

Excerpts from other source:

Dandelion Herbal use and Medicinal Properties

The whole plant is used as a medicinal herb internally and externally.

External Uses

The fresh juice of Dandelion is applied externally to fight bacteria and help heal wounds. The plant has an antibacterial action, inhibiting the growth of Staphococcus aureus, pneumococci, meningococci, Bacillus dysenteriae, B. typhi, C. diphtheriae, proteus. The latex contained in the plant sap can be used to remove corns and warts.

Internal Uses

Dandelion is also used for the treatment of the gall bladder, kidney and urinary disorders, gallstones, jaundice, cirrhosis, hypoglycemia, dyspepsia with constipation, edema associated with high blood pressure and heart weakness, chronic joint and skin complaints, gout, eczema and acne. As a tonic, Dandelion strengthens the kidneys. An infusion of the root encourages the steady elimination of toxins from the body. Dandelion is a powerful diuretic but does not deplete the body of potassium.

Research is revealing that the many constituents of Dandelion including Taraxacin, Taraxacoside, Inulin, Phenolic acids, Sesquiterpene lactones, Triterpenes, Coumarins, Catortenoids and Minerals, mainly Potassium and calcium, are very valuable in curing a number of disorders and illnesses. Dandelion is traditionally used as a tonic and blood purifier, for constipation, inflammatory skin conditions, joint pain, eczema and liver dysfunction, including liver conditions such as hepatitis and jaundice.

Other Uses

When placed in a paper bag with unripe fruit, the flowers and leaves of Dandelion release ethylene gas ripening the fruit quickly. A liquid plant food is made from the root and leaves. A dark red dye is obtained from Dandelion root. A cosmetic skin lotion made from the appendages at the base of the leaf blades distilled in water, is used to clear the skin and is effective in fading freckles.

Main sources:


Blog Stats

  • 533,294 hits