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Chemical constituents
Rich in tannin: fruit, 14 to 17 %; leaves 13 %; bark, 10%.
Corrosolic acid is being studied for its glucose lowering effect.
Parts utilized
Leaves, fruits, flowers and bark.
Uses
Folkloric
– Roots have been used for a variety of stomach ailments. Leaf decoction for diabetes; also use as a diuretic and purgative.
– Decoction of old leaves and dried fruit (dried from one to two weeks), 50 gms to a pint of boiling water, 4 to 6 cups daily has been used for diabetes. Old leaves and ripe fruit are preferred, believed to have greater glucose lowering effect. Young leaves and flowers have a similar effect, though only 70% that of matures leaves and fruits. The wood has no known glucose lowering effect; the bark, a very small amount. A decoction of 20 gms of old leaves or dried fruit in 100 cc of water was found to have the equivalent effect to that of 6 to 7.7 units of insulin.
– The bark decoction has been used for the treatment of diarrhea.
– The bark, flowers and leaves used to facilitiate bowel movements.
– Decoction of fruits or roots gargled for aphthous stomatitis.
– Decoction of leaves and flowers used for fevers and as diuretic.
– Leaf decoction or infusion used for bladder and kidney inflammation, dysuria, and other urinary dysfunctions.
Studies
• Diabetes: (1) Banaba is being studied for its application in the treatment of diabetes. Its ability to lower blood sugar is attributed to its corosolic acid, a triterpenoid glycoside, belived to facilitate glucose-transport into cells. (2) Studied with abutra, akapulko, makabuhay for antidiabetic activity through activation of gucose transporter activity. One of the active principles from Banaba was the tripertene, corosoric aicd.
• Weight loss: Studies in mice suggest an antiobesity effect. It is becoming a common ingredient in weight-loss supplements / products as a metabolic enhancer.
• Hypertension: It is also being studied for its use in the treatment of blood pressure, renal and immune system benefits. • Lipid-lowering: Studies in mice suggest a lipid lowering effect – decreasing triglyceride and total cholesterol levels. To date, no toxicity has been identified.
• Hypoglycemic Activity of Irradiated Banaba Leaves: Study showed the effects of nBLE and iBLE were comparable to the hypoglycemic effects of insulin.
• Xanthine oxidase inhibitors from the leaves of Lagerstroemia speciosa (L.) Pers: Xanthine oxidase is a key enzyme involved with hyperuricemia, catalyzing the oxidation of hypoxanthine to xanthine to uric aicd. The study supports the dietary use of the aqueous extracts from Banaba leaves for the prevention and treatment of hyperuricemia.
• Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics a dose-dependence study: Study showed a significant reduction of blood glucose levels with the soft gel formulation showing better bioavailability than a dry-powder formulation.
Source: http://www.stuartxchange.org/Banaba.html
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